UPDATE ON RIMADYL: "Of all the ADE reports CVM received in 1998, thirty-nine percent (39%) or 3626 involved Rimadyl�. The number of ADE reports received by CVM for Rimadyl� is considerably more than that received for other animal drugs. For any one ADE report, there is no absolute certainty that the suspected drug caused the effect. The adverse effects in these reports are consistent with those expected for NSAIDs. They typically involve the gastrointestinal system, renal/urinary system, hematopoietic (blood) system, neurological system, and the liver. Approximately 13% of the 1998 Rimadyl� ADE reports for dogs involved death of the dog, either on their own or by means of euthanasia."